Title : Interleukin-6 plays a critical role in aldosterone-induced macrophage recruitment and infiltration in the myocardium.

Pub. Date : 2020 Mar 1

PMID : 31785407






4 Functional Relationships(s)
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1 Interleukin-6 plays a critical role in aldosterone-induced macrophage recruitment and infiltration in the myocardium. Aldosterone interleukin 6 Mus musculus
2 We hypothesized that IL-6 may be a key mediator of aldosterone-induced macrophage recruitment and infiltration. Aldosterone interleukin 6 Mus musculus
3 The increase in F4/80-positive cells in the myocardium was suppressed in the aldosterone-infused mice with the aldosterone antagonist eplerenone or anti-IL-6 antibody treatment. Aldosterone interleukin 6 Mus musculus
4 In conclusion, interleukin-6 played an important role in aldosterone-induced macrophage recruitment and infiltration in the myocardium. Aldosterone interleukin 6 Mus musculus