Pub. Date : 2020 Jan
PMID : 31765938
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chronic myelogenous leukemia (CML) is caused by the BCR-ABL chimeric tyrosine kinase, which is derived from the reciprocal translocation, t(9;22)(q34;q11). | Tyrosine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 2 | BCR-ABL tyrosine kinase inhibitors (TKIs) can provide prolonged overall survival in CML patients, resulting in life expectancy nearly to general population, and now approximately half of patients who achieved deep molecular response (DMR) can sustain durable molecular remission after discontinuation TKIs. | Tyrosine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |