Title : AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy.

Pub. Date : 2020 Feb

PMID : 31746509






1 Functional Relationships(s)
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1 mTOR inhibition by rapamycin reversed negative effects of high glucose concentrations on HBV replication, suggesting that low glucose concentration promotes HBV replication by stimulating the AMPK/mTOR-ULK1-autophagy axis. Sirolimus protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens