Title : Sensitization of HT29 colorectal cancer cells to vemurafenib in three-dimensional collagen cultures.

Pub. Date : 2020 Feb

PMID : 31736196






1 Functional Relationships(s)
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1 Further, in cells cultured on TC plastic, vemurafenib was found to augment tyrosine phosphorylation of FAK, while 3D-cultured cells expressed lower levels of FAK and vemurafenib did not affect its tyrosine phosphorylation, suggesting that FAK contributes to vemurafenib resistance. Tyrosine protein tyrosine kinase 2 Homo sapiens