Title : Ligand-dependent inequivalence of the α and β subunits of ferric human hemoglobin bound to haptoglobin.

Pub. Date : 2020 Jan

PMID : 31733428






1 Functional Relationships(s)
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1 However, a variation between tetrameric Hb(III) on one side and Hp1-1:Hb(III), Hp2-2:Hb(III), alpha(III), and beta(III) on the other side for the rate-limiting step (likely referable to the dissociation of heme-coordinated H2O from the heme-Fe(III) atom) suggests a structural change(s) upon dimers to tetramer assembly in Hb(III). Iron chromobox 5 Homo sapiens