Pub. Date : 2020 Feb 1
PMID : 31730885
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In present study, we used benzo[a]pyrene (BaP), a classic and potent ligand of AhR, to activate AhR pathway causes overexpression of the estrogen-metabolizing enzyme cytochrome P450 1A1 (CYP1A1) and affects the expression of important genes involved in hepatic lipid regulation. | Benzo(a)pyrene | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 2 | In present study, we used benzo[a]pyrene (BaP), a classic and potent ligand of AhR, to activate AhR pathway causes overexpression of the estrogen-metabolizing enzyme cytochrome P450 1A1 (CYP1A1) and affects the expression of important genes involved in hepatic lipid regulation. | Benzo(a)pyrene | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 3 | In present study, we used benzo[a]pyrene (BaP), a classic and potent ligand of AhR, to activate AhR pathway causes overexpression of the estrogen-metabolizing enzyme cytochrome P450 1A1 (CYP1A1) and affects the expression of important genes involved in hepatic lipid regulation. | Benzo(a)pyrene | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 4 | In present study, we used benzo[a]pyrene (BaP), a classic and potent ligand of AhR, to activate AhR pathway causes overexpression of the estrogen-metabolizing enzyme cytochrome P450 1A1 (CYP1A1) and affects the expression of important genes involved in hepatic lipid regulation. | Benzo(a)pyrene | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 5 | BaP induces CYP1A1 expression through AhR signaling and inhibits the protective effect of 17beta-estradiol (E2) on hepatic steatosis, characterized by triglyceride accumulation, and markers of liver damage are significantly elevated. | Benzo(a)pyrene | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |