Pub. Date : 2020 Jun
PMID : 31729029
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Human TRPM8 expressed in HEK293T cells is constitutively tyrosine phosphorylated by Src which is expressed either heterologously or endogenously. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 3 | Src action on TRPM8 potentiates its activity, as treatment with PP2, a selective Src kinase inhibitor, reduces both TRPM8 tyrosine phosphorylation and cold-induced channel activation. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 4 | Src action on TRPM8 potentiates its activity, as treatment with PP2, a selective Src kinase inhibitor, reduces both TRPM8 tyrosine phosphorylation and cold-induced channel activation. | Tyrosine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |