Title : Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation.

Pub. Date : 2020 Feb

PMID : 31727674






1 Functional Relationships(s)
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1 Abiraterone acetate (AA) is a prodrug of abiraterone (Abi), a CYP17A1 inhibitor used to treat patients with advanced prostate cancer (PCa). abiraterone acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens