Title : Metabolic Activation of Tofacitinib Mediated by Myeloperoxidase in Vitro.

Pub. Date : 2019 Dec 16

PMID : 31725283






2 Functional Relationships(s)
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1 The present study demonstrated that TFT was oxidized to a chemically reactive nitrenium ion by myeloperoxidase (MPO) occurring in neutrophils. nitrenium myeloperoxidase Homo sapiens
2 The present study demonstrated that TFT was oxidized to a chemically reactive nitrenium ion by myeloperoxidase (MPO) occurring in neutrophils. nitrenium myeloperoxidase Homo sapiens