Title : Orexin-A Excites Airway Vagal Preganglionic Neurons via Activation of Orexin Receptor Type 1 and Type 2 in Rats.

Pub. Date : 2019

PMID : 31708749






2 Functional Relationships(s)
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1 In synaptically isolated IA-AVPNs, the depolarization induced by orexin-A was blocked partially by OX1R antagonist SB-334867 or OX2R antagonist TCS OX2 29 alone, and completely by co-application of both antagonists. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide hypocretin neuropeptide precursor Rattus norvegicus
2 Orexin-A facilitated the glutamatergic, glycinergic and GABAergic inputs to IA-AVPNs, and the facilitation of each type of input was blocked partially by SB-334867 or TCS OX2 29 alone, and completely by co-application of both antagonists. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide hypocretin neuropeptide precursor Rattus norvegicus