| Protein Name | hypocretin neuropeptide precursor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25723 |
| Gene Symbol | Hcrt |
| UniProt | O55232 (OREX_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
325
Total Number of Articles : 603 |
Description |
hypocretin neuropeptide precursor |
| Gene Summary |
Enables neuropeptide hormone activity; type 1 orexin receptor binding activity; and type 2 orexin receptor binding activity. Involved in several processes, including behavioral response to ethanol; regulation of metal ion transport; and regulation of transmission of nerve impulse. Located in secretory granule. Is active in neuronal dense core vesicle lumen. Biomarker of hyperglycemia; obesity; and sleeping sickness. Human ortholog(s) of this gene implicated in heroin dependence and narcolepsy. Orthologous to human HCRT (hypocretin neuropeptide precursor). [provided by Alliance of Genome Resources, Jun 2025] |
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