Title : Benzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitro.

Pub. Date : 2020 Feb 1

PMID : 31707104






1 Functional Relationships(s)
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1 Benzalkonium chloride (BAK), a quaternary ammonium compound widely used as disinfecting agent as well as preservative in eye drops is known to induce toxic effects on the ocular surface with inflammation and corneal nerve damage leading to dry eye disease (DED) in the medium-to-long term. quaternary ammonium BCL2 antagonist/killer 1 Homo sapiens