Title : Cell proliferation and invasion are regulated differently by EGFR and MRP1 in T-DM1-resistant breast cancer cells.

Pub. Date : 2019 Nov 8

PMID : 31704984






1 Functional Relationships(s)
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1 Downregulating EGFR and MRP1 inhibits T-DM1R-JIMT1 cell growth and re-sensitizes T-DM1R cells to doxorubicin, suggesting that dual targeting EGFR and MRP1 could serve as a therapeutic approach to overcome T-DM1 resistance. Doxorubicin ATP binding cassette subfamily C member 1 Homo sapiens