Title : Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene.

Pub. Date : 2019 Dec

PMID : 31699670






2 Functional Relationships(s)
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1 Exposure of BV2 cells to BaP (10 muM) significantly increased DNA damage and the production of pro-inflammatory mediators, including nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), reactive oxygen species (ROS), malondialdehyde (MDA), and cytokines (interleukins-1beta and -6). Benzo(a)pyrene prostaglandin-endoperoxide synthase 2 Mus musculus
2 Exposure of BV2 cells to BaP (10 muM) significantly increased DNA damage and the production of pro-inflammatory mediators, including nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), reactive oxygen species (ROS), malondialdehyde (MDA), and cytokines (interleukins-1beta and -6). Benzo(a)pyrene prostaglandin-endoperoxide synthase 2 Mus musculus