Title : Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis.

Pub. Date : 2020 Jan 5

PMID : 31697926






1 Functional Relationships(s)
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1 Over expression of TLR4/MyD88/NFkappaB axis and its downstream pro-inflammatory mediators TNF-alpha, IL6 and IFN-gamma were observed in CCl4 induced mice, and these indices were abrogated significantly after GA treatment. ginkgolide A toll-like receptor 4 Mus musculus