Title : Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington's disease.

Pub. Date : 2019 Nov 6

PMID : 31695068






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ribosomal protein S6 kinase 1 (S6K1) is a major downstream signalling molecule of mTOR, and its activity is reduced by rapamycin suggesting that deregulation of S6K1 activity may be beneficial in HD. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens
2 Ribosomal protein S6 kinase 1 (S6K1) is a major downstream signalling molecule of mTOR, and its activity is reduced by rapamycin suggesting that deregulation of S6K1 activity may be beneficial in HD. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens