Title : Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population.

Pub. Date : 2019 Nov 5

PMID : 31690757






3 Functional Relationships(s)
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1 Regarding MDR1 gene, the plasma concentration of midazolam was greater in patients with CGC haplotype (P = 0.012), while it was lower in patients with CAC haplotype (P = 0.005) than in those with other haplotypes. Midazolam ATP binding cassette subfamily B member 1 Homo sapiens
2 CGT haplotype of MDR1 was significantly correlated with sedation grade after midazolam administration (P = 0.042). Midazolam ATP binding cassette subfamily B member 1 Homo sapiens
3 Genetic polymorphism of MDR1 influences the concentration of midazolam and the sedation grade. Midazolam ATP binding cassette subfamily B member 1 Homo sapiens