Title : 6-Shogaol, an active ingredient of ginger, inhibits osteoclastogenesis and alveolar bone resorption in ligature-induced periodontitis in mice.

Pub. Date : 2020 Jun

PMID : 31675438






1 Functional Relationships(s)
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1 In the presence of 6-shogaol, osteoclast signaling including the RANKL-induced activation of mitogen-activated protein kinases, Ca2+ oscillation, generation of reactive oxygen species, and nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1) nuclear translocation was significantly inhibited in vitro. Oxygen tumor necrosis factor (ligand) superfamily, member 11 Mus musculus