Title : Cross-linking of proteins by aldotriose: reaction of the carbonyl function of the keto amines generated in situ with amino groups.

Pub. Date : 1988 Jun 14

PMID : 3166996






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Reaction of RNase A (0.5 mM) with glyceraldehyde (20 mM) at pH 7.4 and 37 degrees C for 4 h resulted in the intermolecular cross-linking of the protein, with the concomitant development of a yellow chromophore with two new absorption bands having maxima around 305 and 375 nm. Glyceraldehyde ribonuclease A family member 1, pancreatic Homo sapiens
2 The cross-linking reaction was inhibited when the reaction of RNase A with glyceraldehyde was carried out in the presence of amino compounds, such as glycine ethyl ester, ethanolamine, glucosamine, and aminoguanidine. Glyceraldehyde ribonuclease A family member 1, pancreatic Homo sapiens