Title : Intestinal breast cancer resistance protein (BCRP) requires Janus kinase 3 activity for drug efflux and barrier functions in obesity.

Pub. Date : 2019 Nov 29

PMID : 31653704






2 Functional Relationships(s)
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1 We demonstrate that the compromised BCRP functions during obesity are due to loss of Janus kinase 3 (JAK3)-mediated tyrosine phosphorylation of BCRP. Tyrosine ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens
2 We demonstrate that the compromised BCRP functions during obesity are due to loss of Janus kinase 3 (JAK3)-mediated tyrosine phosphorylation of BCRP. Tyrosine ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens