Title : Role for protein kinase C in the modulation of glomerular PGE2 production by angiotensin II.

Pub. Date : 1988 May 16

PMID : 3163921






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 12-O-Tetradecanoyl phorbol -13-acetate (TPA, 10(-7) M), which stimulates protein kinase C activity in soluble fractions of glomerular homogenates, suppressed angiotensin II actions on inositol phosphate production and PGE2. Tetradecanoylphorbol Acetate angiotensinogen Homo sapiens
2 12-O-Tetradecanoyl phorbol -13-acetate (TPA, 10(-7) M), which stimulates protein kinase C activity in soluble fractions of glomerular homogenates, suppressed angiotensin II actions on inositol phosphate production and PGE2. Tetradecanoylphorbol Acetate angiotensinogen Homo sapiens
3 1-(5-Isoquinolinyl)-2-methylpiperazine (H-7), which inhibits protein kinase C activity in soluble fractions of glomerular homogenates, prevented TPA induced suppression of angiotensin II actions on inositol phosphate production and PGE2. Tetradecanoylphorbol Acetate angiotensinogen Homo sapiens