Pub. Date : 2019 Dec
PMID : 31638830
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier. | Dinoprostone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Thus, we hypothesized that inhibiting microsomal prostaglandin E2 (PGE2) synthase-1 (mPGES-1), the enzyme generating PGE2, prevents blood-brain barrier P-gp up-regulation after status epilepticus (SE). | Dinoprostone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Thus, we hypothesized that inhibiting microsomal prostaglandin E2 (PGE2) synthase-1 (mPGES-1), the enzyme generating PGE2, prevents blood-brain barrier P-gp up-regulation after status epilepticus (SE). | Dinoprostone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Thus, we hypothesized that inhibiting microsomal prostaglandin E2 (PGE2) synthase-1 (mPGES-1), the enzyme generating PGE2, prevents blood-brain barrier P-gp up-regulation after status epilepticus (SE). | Dinoprostone | ATP binding cassette subfamily B member 1 | Homo sapiens |