Title : Identification of Crucial Residues in α-Conotoxin EI Inhibiting Muscle Nicotinic Acetylcholine Receptor.

Pub. Date : 2019 Oct 16

PMID : 31623211






1 Functional Relationships(s)
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1 In addition, the structure-activity relationship (SAR) of EI revealed that the "Arg1-Asn2-Hyp3" residues at the N-terminus conferred potency at the muscle-type nAChRs, and the deletion analogue 1-3 EI caused a total loss of activity at the alpha1beta1deltaepsilon nAChR. Nitrogen cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus