Title : Site-Specific Encoding of Photoactivity in Antibodies Enables Light-Mediated Antibody-Antigen Binding on Live Cells.

Pub. Date : 2019 Dec 9

PMID : 31609054






1 Functional Relationships(s)
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1 Presence of photocaged tyrosine reduces 7D12-EGFR binding affinity by over 20-fold in two out of three 7D12 mutants studied, and binding is restored upon exposure to 365 nm light. Tyrosine epidermal growth factor receptor Homo sapiens