Title : Structural Perturbations due to Mutation (H1047R) in Phosphoinositide-3-kinase (PI3Kα) and Its Involvement in Oncogenesis: An in Silico Insight.

Pub. Date : 2019 Oct 1

PMID : 31592171






2 Functional Relationships(s)
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Protein Name
Organism
1 Oncogenic mutation in the catalytic subunit p110alpha of PI3Kalpha at the 1047 position in the kinase domain substitutes the histidine with arginine. histidine-pyridine-histidine-3 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens
2 Oncogenic mutation in the catalytic subunit p110alpha of PI3Kalpha at the 1047 position in the kinase domain substitutes the histidine with arginine. histidine-pyridine-histidine-3 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens