Title : Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide.

Pub. Date : 2020 Apr

PMID : 31587305






1 Functional Relationships(s)
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1 Other studies have shown that knockdown of RB1 and TP53 increases the expression of neuroendocrine markers, decreases the sensitivity to enzalutamide, and increases the expression of SOX2. enzalutamide RB transcriptional corepressor 1 Homo sapiens