Pub. Date : 2019 Dec 1
PMID : 31569004
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Discovery of 2-aminopyridines bearing a pyridone moiety as potent ALK inhibitors to overcome the crizotinib-resistant mutants. | crizotinib | ALK receptor tyrosine kinase | Homo sapiens |
| 2 | Taken together, this work provided a promising ALK inhibitor to circumvent the clinical crizotinib-resistant mutants. | crizotinib | ALK receptor tyrosine kinase | Homo sapiens |