Title : Fabrication and characterization of solid lipid nano-formulation of astraxanthin against DMBA-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway.

Pub. Date : 2019 Dec

PMID : 31556759






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 AX-SLN reduced the p-AKT which is accountable for the reduction in the NF-kB expression and also reduced the expression of Keap1 and NF-kB along with increasing the expression of HO-1 and Nrf-2. Amoxicillin kelch like ECH associated protein 1 Homo sapiens
2 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin kelch like ECH associated protein 1 Homo sapiens