Title : Icariside II inhibits lipopolysaccharide-induced inflammation and amyloid production in rat astrocytes by regulating IKK/IκB/NF-κB/BACE1 signaling pathway.

Pub. Date : 2020 Feb

PMID : 31554962






1 Functional Relationships(s)
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1 Moreover, ICS II not only exerted the inhibitory effect on LPS-induced IkappaB-alpha degradation and NF-kappaB activation, but also decreased the levels of Abeta1-40, Abeta1-42, amyloid precursor protein (APP) and beta secretase 1 (BACE1) in the astrocytes. baohuoside I amyloid beta precursor protein Rattus norvegicus