Pub. Date : 2019 Sep
PMID : 31539112
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Long non-coding RNA ROR regulated ABCB1 to induce cisplatin resistance in osteosarcoma by sponging miR-153-3p. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | PATIENTS AND METHODS: The levels of ROR, miR-153-3p, and ABCB1 in cisplatin-resistant OS tissues and cells were detected by qRT-PCR and/or Western blot assay. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | CONCLUSIONS: We found that ROR or ABCB1 knockdown can increase the cisplatin sensitivity of MG63/DDP and U2OS/DDP cells. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | ROR contributed to cisplatin resistance in OS via miR-153-3p/ABCB1 axis, unraveling a new regulatory network of chemoresistance in cisplatin-resistant OS cells and may provide a therapeutic target for OS patients. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | ROR contributed to cisplatin resistance in OS via miR-153-3p/ABCB1 axis, unraveling a new regulatory network of chemoresistance in cisplatin-resistant OS cells and may provide a therapeutic target for OS patients. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |