Title : Gp130 degradation induced by epirubicin contributes to chemotherapy efficacy.

Pub. Date : 2019 Nov 12

PMID : 31537377






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Epirubicin induces activation of p38-MK2 signaling pathway to phosphorylate gp130 at Ser 782, which results in gp130 internalization and degradation by lysosome. Serine mitogen-activated protein kinase 14 Homo sapiens