Title : Alcohol's Dysregulation of Maternal-Fetal IL-6 and p-STAT3 Is a Function of Maternal Iron Status.

Pub. Date : 2019 Nov

PMID : 31524964






3 Functional Relationships(s)
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1 Alcohol"s dysregulation of maternal-fetal IL-6 and p-STAT3 is a function of maternal iron status. Iron interleukin 6 Rattus norvegicus
2 Here, we hypothesize that iron status and PAE dysregulate the major upstream pathways that govern hepcidin production - EPO/BMP6/SMAD and IL-6/JAK2/STAT3. Iron interleukin 6 Rattus norvegicus
3 Dietary iron fortification sharply attenuated Il-6 expression in response to PAE, with IF driving a 150-fold decrease (P<0.001) in maternal liver and a 10-fold decrease (P<0.01) in fetal liver. Iron interleukin 6 Rattus norvegicus