Title : Serotonin and serotonin reuptake inhibitors alter placental aromatase.

Pub. Date : 2019 Dec

PMID : 31509772






1 Functional Relationships(s)
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1 Based on molecular simulations, the present study illustrates that the SRIs fluoxetine, norfluoxetine, paroxetine, sertraline, citalopram and venlafaxine exhibit binding affinity for the active-site pocket of CYP19, suggesting potential competitive inhibition. Paroxetine cytochrome P450 family 19 subfamily A member 1 Homo sapiens