Pub. Date : 2019 Dec
PMID : 31509771
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 17A1 (CYP17A1) catalyses the 17alpha-hydroxylation and 17,20 lyase reactions to convert pregnenolone to 17alpha-hydroxypregnenolone (17OHP) and subsequently the androgen dehydroepiandrosterone (DHEA). | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Cytochrome P450 17A1 (CYP17A1) catalyses the 17alpha-hydroxylation and 17,20 lyase reactions to convert pregnenolone to 17alpha-hydroxypregnenolone (17OHP) and subsequently the androgen dehydroepiandrosterone (DHEA). | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 3 | Cytochrome P450 17A1 (CYP17A1) catalyses the 17alpha-hydroxylation and 17,20 lyase reactions to convert pregnenolone to 17alpha-hydroxypregnenolone (17OHP) and subsequently the androgen dehydroepiandrosterone (DHEA). | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 4 | Cytochrome P450 17A1 (CYP17A1) catalyses the 17alpha-hydroxylation and 17,20 lyase reactions to convert pregnenolone to 17alpha-hydroxypregnenolone (17OHP) and subsequently the androgen dehydroepiandrosterone (DHEA). | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 5 | We have identified and mutated residues in porcine CYP17A1 and CYB5A that may alter the synthesis of DHEA and 16A. | Dehydroepiandrosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |