Title : Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling.

Pub. Date : 2019 Sep

PMID : 31495720






2 Functional Relationships(s)
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1 Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling. Cisplatin CD274 molecule Homo sapiens
2 Although Scribble deficiency tends to lead to cisplatin resistance by Nox2/ROS and Nrf2/PD-L1, it is still possible that Scribble deficiency-induced PD-L1 may yield benefits in immunotherapy. Cisplatin CD274 molecule Homo sapiens