Title : PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain.

Pub. Date : 2019 Aug 13

PMID : 31452836






3 Functional Relationships(s)
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1 Furthermore, PTEN dephosphorylates Pol II CTD in vitro with a significant specificity for Ser5p. ser5p phosphatase and tensin homolog Homo sapiens
2 Interestingly, ChIP-seq data analysis revealed that PTEN globally binds to promoter proximal regions, and PTEN loss increases genome-wide Pol II Ser5p occupancy, suggest that PTEN is a Pol II CTD phosphatase. ser5p phosphatase and tensin homolog Homo sapiens
3 Interestingly, ChIP-seq data analysis revealed that PTEN globally binds to promoter proximal regions, and PTEN loss increases genome-wide Pol II Ser5p occupancy, suggest that PTEN is a Pol II CTD phosphatase. ser5p phosphatase and tensin homolog Homo sapiens