Title : Doxorubicin induces cardiomyocyte pyroptosis via the TINCR-mediated posttranscriptional stabilization of NLR family pyrin domain containing 3.

Pub. Date : 2019 Nov

PMID : 31445005






1 Functional Relationships(s)
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1 METHODS AND RESULTS: In vitro and in vivo experiments showed that DOX treatment induced cardiomyocyte pyroptosis as evidenced by increased cell death and upregulated expression levels of NLR family pyrin domain containing 3 (NLRP3), caspase-3, IL-1beta, IL-18 and GMDSD-N. Doxorubicin interleukin 18 Homo sapiens