Title : Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types.

Pub. Date : 2020 Jun

PMID : 31439679






2 Functional Relationships(s)
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1 Compared to other cell types, CD19+/B and CD56+/NK cells were more sensitive to dexamethasone, venetoclax and midostaurin, while monocytes were more sensitive to trametinib. midostaurin CD19 molecule Homo sapiens
2 Lineage specific effect of midostaurin was similarly detected in CD19+/B cells from healthy, acute myeloid leukemia and chronic lymphocytic leukemia samples. midostaurin CD19 molecule Homo sapiens