Title : BCR-ABL induces tyrosine phosphorylation of YAP leading to expression of Survivin and Cyclin D1 in chronic myeloid leukemia cells.

Pub. Date : 2019 Nov

PMID : 31428968






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BCR-ABL induces tyrosine phosphorylation of YAP leading to expression of Survivin and Cyclin D1 in chronic myeloid leukemia cells. Tyrosine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 These results suggest that BCR-ABL induces tyrosine phosphorylation of YAP presumably through Src family kinases, which results in expression of Survivin and Cyclin D leading to leukemogenesis in CML cells. Tyrosine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens