Title : Bioanalytical evaluation of dried plasma spots for monitoring of abiraterone and ∆(4)-abiraterone from cancer patients.

Pub. Date : 2019 Sep 15

PMID : 31421381






1 Functional Relationships(s)
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1 In vivo, the prodrug is readily metabolized to abiraterone and its active metabolite Delta(4)-abiraterone (D4A) which selectively and irreversibly inhibit the 17alpha-hydroxylase/17,20-lyase (CYP17A1) enzyme and the androgen receptor, respectively. abiraterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens