Title : Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia.

Pub. Date : 2019 Oct 10

PMID : 31395602






1 Functional Relationships(s)
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1 Both biochemistry and computational analysis demonstrate that R972/973 methylation could facilitate recruitment of adaptor proteins to FLT3 in a phospho-tyrosine (Y) residue 969 dependent or independent manner. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens