Pub. Date : 2019 Sep 5
PMID : 31375263
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The oligomerization is induced when the ZZ domain of p62 is bound by the N-terminal arginine (Nt-Arg) of arginylated substrates. | nt-arg | sequestosome 1 | Homo sapiens |
| 2 | Upon activation by the Nt-Arg, oligomerized TRIM13-p62 complexes are separated along with the ER compartments and targeted to autophagosomes, leading to lysosomal degradation. | nt-arg | sequestosome 1 | Homo sapiens |