Title : Kidney Injury Molecule-1 Is Upregulated in Renal Lipotoxicity and Mediates Palmitate-Induced Tubular Cell Injury and Inflammatory Response.

Pub. Date : 2019 Jul 11

PMID : 31373312






1 Functional Relationships(s)
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1 In cultured primary renal tubular epithelial cells (TECs), administration of saturated fatty acid palmitate resulted in an upregulation of KIM-1, osteopontin, and CD44, which was greatly attenuated by U0126, an inhibitor of extracellular signal-regulated kinase (ERK)1/2. saturated fatty acid palmitate CD44 molecule (Indian blood group) Rattus norvegicus