Protein Name CD44 molecule
Organism Rattus norvegicus
Gene ID 25406
Gene Symbol

Cd44

UniProt P26051 (CD44_RAT), O70509 (O70509_RAT), O08779 (O08779_RAT)
Relationships Total Number of functionally related compound(s) : 94
Total Number of Articles : 120
Description

CD44 molecule

Gene Summary

Enables epidermal growth factor receptor binding activity; phosphoprotein binding activity; and protein kinase binding activity. Involved in several processes, including blood vessel maturation; macrophage fusion; and positive regulation of neutrophil apoptotic process. Located in apical plasma membrane; basolateral plasma membrane; and cell surface. Part of protein-containing complex. Is active in glutamatergic synapse; postsynapse; and presynapse. Biomarker of borna disease and cholestasis. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • CD44 antigen
  • CD44 molecule (Indian blood group)
  • Cell surface glycoprotein CD44 (hyaluronate binding protein)
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Properties