Pub. Date : 2019
PMID : 31371987
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Long noncoding RNA DANCR contributes to docetaxel resistance in prostate cancer through targeting the miR-34a-5p/JAG1 pathway. | Docetaxel | jagged canonical Notch ligand 1 | Homo sapiens |
| 2 | DANCR served as a competing endogenous RNA of miR-34a-5p, leading to the derepression of miR-34a-5p target JAG1, which eventually triggered the resistance to DTX in DTX-tolerated PC. | Docetaxel | jagged canonical Notch ligand 1 | Homo sapiens |
| 3 | DANCR served as a competing endogenous RNA of miR-34a-5p, leading to the derepression of miR-34a-5p target JAG1, which eventually triggered the resistance to DTX in DTX-tolerated PC. | Docetaxel | jagged canonical Notch ligand 1 | Homo sapiens |
| 4 | Conclusion: The DANCR/miR-34a-5p axis enhanced DTX resistance of PC via targeting JAG1, providing a novel insight to improve chemotherapy for PC. | Docetaxel | jagged canonical Notch ligand 1 | Homo sapiens |