Title : Mitophagy protects against statin-mediated skeletal muscle toxicity.

Pub. Date : 2019 Nov

PMID : 31365836






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1 Here we demonstrate that simvastatin induces mitophagy in skeletal muscle cells and hypothesized that attenuating this process by silencing the mitophagy adapter p62/sequestosome-1 (SQSTM1) might mitigate myotoxicity. Simvastatin sequestosome 1 Mus musculus