Title : Betulinic acid attenuates lipopolysaccharide-induced vascular hyporeactivity in the rat aorta by modulating Nrf2 antioxidative function.

Pub. Date : 2020 Feb

PMID : 31352642






1 Functional Relationships(s)
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1 Increases of IL-1beta, TNF-alpha, nitric oxide, and malondialdehyde and the decrease of glutathione induced by LPS were significantly attenuated by pretreatment with different doses of BA in plasma and aortas (p < 0.05 versus LPS), all of which were blocked by Bru (p < 0.01). betulinic acid tumor necrosis factor Rattus norvegicus