Title : Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes.

Pub. Date : 2019 Jul 22

PMID : 31332162






1 Functional Relationships(s)
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1 These results indicate that SLAMF3 upregulation is associated with T-cell activation and cytokine production in T2D patients, and suggest that elevated saturated fatty acids in T2D patients may induce SLAMF3 upregulation on T cells via activation of the STAT5-PI3K/Akt signaling pathway. Fatty Acids AKT serine/threonine kinase 1 Homo sapiens