Title : Effects of resveratrol on VEGF & HIF1 genes expression in granulosa cells in the angiogenesis pathway and laboratory parameters of polycystic ovary syndrome: a triple-blind randomized clinical trial.

Pub. Date : 2019 Aug

PMID : 31327131






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1 Effects of resveratrol on VEGF & HIF1 genes expression in granulosa cells in the angiogenesis pathway and laboratory parameters of polycystic ovary syndrome: a triple-blind randomized clinical trial. Resveratrol hypoxia inducible factor 1 subunit alpha Homo sapiens
2 The results showed a reduction in the expression of VEGF & HIF1 genes under the effect of resveratrol in the granulosa cells (P = 0.0001). Resveratrol hypoxia inducible factor 1 subunit alpha Homo sapiens
3 CONCLUSIONS: Based on the results, resveratrol may improve some outcomes of PCOS patients, probably through changing the serum levels of some sex hormones and expression of VEGF & HIF1 genes in the angiogenesis pathway of granulosa cells. Resveratrol hypoxia inducible factor 1 subunit alpha Homo sapiens