Pub. Date : 2019 Jul 15
PMID : 31311167
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | De-regulation of the poly(ADP-ribose) polymerase 1 (PARP1)/high-mobility group box 1 (HMGB1) signaling pathway has been proposed as an important mechanism involved in cisplatin-resistance. | Cisplatin | high mobility group box 1 | Homo sapiens |
| 2 | De-regulation of the poly(ADP-ribose) polymerase 1 (PARP1)/high-mobility group box 1 (HMGB1) signaling pathway has been proposed as an important mechanism involved in cisplatin-resistance. | Cisplatin | high mobility group box 1 | Homo sapiens |
| 3 | The cisplatin/Morin hydrate combination was effective in the reversal of the HepG2DR cell resistance via suppression of PARP1-mediated autophagy by regulating the HMGB1 and microtubule-associated protein 1A/1B light chain 3B (LC3) I/II. | Cisplatin | high mobility group box 1 | Homo sapiens |